Genetic Drift in an Outbred Stock of Mice
نویسندگان
چکیده
منابع مشابه
development and implementation of an optimized control strategy for induction machine in an electric vehicle
in the area of automotive engineering there is a tendency to more electrification of power train. in this work control of an induction machine for the application of electric vehicle is investigated. through the changing operating point of the machine, adapting the rotor magnetization current seems to be useful to increase the machines efficiency. in the literature there are many approaches wh...
15 صفحه اولHigh-Resolution Mapping of Gene Expression Using Association in an Outbred Mouse Stock
Quantitative trait locus (QTL) analysis is a powerful tool for mapping genes for complex traits in mice, but its utility is limited by poor resolution. A promising mapping approach is association analysis in outbred stocks or different inbred strains. As a proof of concept for the association approach, we applied whole-genome association analysis to hepatic gene expression traits in an outbred ...
متن کاملMOUSE GENETIC RESOURCES Genome-Wide Association Mapping of Quantitative Traits in Outbred Mice
Recent developments in high-density genotyping and statistical analysis methods that have enabled genome-wide association studies in humans can also be applied to outbred mouse populations. Increased recombination in outbred populations is expected to provide greater mapping resolution than traditional inbred line crosses, improving prospects for identifying the causal genes. We carried out gen...
متن کاملExperimental Borrelia burgdorferi infection of outbred mice.
Infectivity of Borrelia burgdorferi strain 297 in normal outbred ddY mice was examined. Strain 297 was inoculated intraperitoneally in 3-week-old outbred ddY mice. B. burgdorferi was routinely cultured from the heart and urinary bladder 5 to 84 days postinoculation. The combined isolation rate from both heart and urinary bladder was significantly higher than the rate from spleen, kidney, liver,...
متن کاملGenetic Management of Outbred Laboratory Rodent Populations
This document describes the Gold Standard populations of outbred laboratory animals that have been developed at Charles River Laboratories. Using modern techniques of population and molecular genetics, the Gold Standard populations are carefully managed in such a way as to preserve genetic variation and to provide a reliable source of outbred animals for experimental use. The Gold Standard anim...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Experimental Animals
سال: 1992
ISSN: 0007-5124,1881-7122
DOI: 10.1538/expanim1978.41.2_215